CBX5
Reactivité: Humain
WB, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. IHC: 1:100. ICC: 1:300
Restrictions
For Research Use only
Format
Liquid
Stock
4 °C,-20 °C
Antigène
CBX5
(Chromobox Homolog 5 (CBX5))
Autre désignation
HP1 alpha
Sujet
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.